PFKM Antibody - C-terminal region : Biotin (ARP61167_P050-Biotin)
Selected Variant
ARP61167_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Phosphofructokinase, muscle
Gene Aliases
GSD7, PFK1, PFKA, PFKX, PFK-1, PFK-A, ATP-PFK, PPP1R122
Gene ID
5213
Swiss Prot
P08237
Accession Number
NP_000280
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PFKM
Target
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Partner Proteins
UBC; SIAH1; PFKM; SUMO2; EGFR; DCP2; DCP1A; TUBB2A; PFKP; PCBP1; UBTD1; FBXO6; LSM7; PFKL; NDUFB2; Hoxa1; CUL3; MAPK3; PCNA; SUMO1; ATP6V0A4; FHL2; DYNLL1; CAV3; NOS1; HGS
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
85kDa
Shipping Conditions
Wet Ice
Protein Length
780
NCBI Gene Symbol
PFKM
NCBI GB Accession Number
PFKM
Host or Source
Rabbit
Protein Name
6-phosphofructokinase, muscle type
Nucleotide Accession Number
NM_000289
Peptide Sequence
RALVFQPVAELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHA
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