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Prom1 Antibody - N-terminal region : FITC (ARP61144_P050-FITC)

Selected Variant

ARP61144_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Prominin 1

Gene Aliases

P, Pro, AC13, Prom, AC133, CD133, Prom-1, Proml1, 4932416E19Rik

Gene ID

19126

Swiss Prot

O54990

Accession Number

NP_001157049

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Target

Prom1 binds cholesterol in cholesterol-containing plasma membrane microdomains. It is rroposed to play a role in apical plasma membrane organization of epithelial cells. During early during retinal development, Prom1 acts as a key regulator of disk morphogenesis. Prom1 is involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

Partner Proteins

Actb

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 85%; Rat: 91%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

95kDa

Shipping Conditions

Wet Ice

Protein Length

867

NCBI Gene Symbol

PROM1

NCBI GB Accession Number

Prom1

Host or Source

Rabbit

Protein Name

Prominin-1

Nucleotide Accession Number

NM_001163577

Peptide Sequence

IILMPLVGCFFCMCRCCNKCGGEMHQRQKQNAPCRRKCLGLSLLVICLLM

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