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CDA Antibody - C-terminal region : Biotin (ARP61133_P050-Biotin)

Selected Variant

ARP61133_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Cytidine deaminase

Gene Aliases

CDD

Gene ID

978

Swiss Prot

P32320

Accession Number

NP_001776

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CDA

Target

This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Partner Proteins

LNX1; C20orf195; WDYHV1; PLEKHB2; ZBTB24; SDCBP; PTGER3; PSMA1; UBC; RC3H1; CDA; ZNF598; KPNA2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Guinea Pig: 92%; Horse: 83%; Human: 100%; Mouse: 86%; Rat: 92%; Yeast: 83%; Zebrafish: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

16kDa

Shipping Conditions

Wet Ice

Protein Length

146

NCBI Gene Symbol

CDA

NCBI GB Accession Number

CDA

Host or Source

Rabbit

Protein Name

Cytidine deaminase

Nucleotide Accession Number

NM_001785

Peptide Sequence

SPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ

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