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GABBR2 Antibody - C-terminal region : HRP (ARP61115_P050-HRP)

Selected Variant

ARP61115_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Gamma-aminobutyric acid (GABA) B receptor, 2

Gene Aliases

HG20, DEE59, GPR51, EIEE59, GPRC3B, NDPLHS, GABABR2, HRIHFB2099

Gene ID

9568

Swiss Prot

O75899

Accession Number

NP_005449

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GABBR2

Target

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.

Partner Proteins

KCTD12; GLP1R; Dlg4; GRASP; ATF4; ATF5; GABBR1; SH3GL3; NSF; HTR1A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

106kDa

Shipping Conditions

Wet Ice

Protein Length

941

NCBI Gene Symbol

GABBR2

NCBI GB Accession Number

GABBR2

Host or Source

Rabbit

Protein Name

Gamma-aminobutyric acid type B receptor subunit 2

Nucleotide Accession Number

NM_005458

Peptide Sequence

QFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLE

Subunit

2

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