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LIPA Antibody - N-terminal region : HRP (ARP61109_P050-HRP)

Selected Variant

ARP61109_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Lipase A, lysosomal acid, cholesterol esterase

Gene Aliases

LAL, CESD

Gene ID

3988

Swiss Prot

P38571

Accession Number

NP_000226

Host

Rabbit

Reactivity

Human, Rat, Cow, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human LIPA

Target

This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase) . This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Partner Proteins

ELAVL1; UBC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

LIPA is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Horse: 86%; Human: 100%; Pig: 100%; Rabbit: 93%; Rat: 86%; Sheep: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

Shipping Conditions

Wet Ice

Protein Length

399

NCBI Gene Symbol

LIPA

NCBI GB Accession Number

LIPA

Host or Source

Rabbit

Protein Name

Lysosomal acid lipase/cholesteryl ester hydrolase

Nucleotide Accession Number

NM_000235

Peptide Sequence

SYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLAD

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