LIPA Antibody - N-terminal region : Biotin (ARP61109_P050-Biotin)
Product Specifications
Gene Name
Lipase A, lysosomal acid, cholesterol esterase
Gene Aliases
LAL, CESD
Gene ID
3988
Swiss Prot
P38571
Accession Number
NP_000226
Host
Rabbit
Reactivity
Human, Rat, Cow, Horse, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human LIPA
Target
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase) . This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Partner Proteins
ELAVL1; UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
LIPA is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/ml
Homology
Cow: 93%; Horse: 86%; Human: 100%; Pig: 100%; Rabbit: 93%; Rat: 86%; Sheep: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
43kDa
Shipping Conditions
Wet Ice
Protein Length
399
NCBI Gene Symbol
LIPA
NCBI GB Accession Number
LIPA
Host or Source
Rabbit
Protein Name
Lysosomal acid lipase/cholesteryl ester hydrolase
Nucleotide Accession Number
NM_000235
Peptide Sequence
SYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLAD
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