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GPI Antibody - C-terminal region : FITC (ARP61089_P050-FITC)

Selected Variant

ARP61089_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Glucose-6-phosphate isomerase

Gene Aliases

AMF, NLK, PGI, PHI, GNPI, SA36, SA-36

Gene ID

2821

Swiss Prot

P06744

Accession Number

NP_000166

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GPI

Target

This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Partner Proteins

HUWE1; ISG15; UBC; FUS; AMFR; MDM2; ASB15; BAG3; TMEM256; PDCD6IP; TPI1; ENO3; SUMO1; SUMO3; CCP110; CDK2; NEURL4; PCNA; AI837181; Csnk1e; GPI; IGFBP3; CSNK2A1; PARP14

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 85%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

63kDa

Shipping Conditions

Wet Ice

Protein Length

558

NCBI Gene Symbol

GPI

NCBI GB Accession Number

GPI

Host or Source

Rabbit

Protein Name

Glucose-6-phosphate isomerase

Nucleotide Accession Number

NM_000175

Peptide Sequence

EALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFTKLT

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