GPI Antibody - C-terminal region : FITC (ARP61088_P050-FITC)
Selected Variant
ARP61088_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Glucose-6-phosphate isomerase
Gene Aliases
AMF, NLK, PGI, PHI, GNPI, SA36, SA-36
Gene ID
2821
Swiss Prot
P06744
Accession Number
NP_000166
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human GPI
Target
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.
Partner Proteins
HUWE1; ISG15; UBC; FUS; AMFR; MDM2; ASB15; BAG3; TMEM256; PDCD6IP; TPI1; ENO3; SUMO1; SUMO3; CCP110; CDK2; NEURL4; PCNA; AI837181; Csnk1e; GPI; IGFBP3; CSNK2A1; PARP14
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 86%; Guinea Pig: 100%; Human: 100%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
63kDa
Shipping Conditions
Wet Ice
Protein Length
558
NCBI Gene Symbol
GPI
NCBI GB Accession Number
GPI
Host or Source
Rabbit
Protein Name
Glucose-6-phosphate isomerase
Nucleotide Accession Number
NM_000175
Peptide Sequence
SFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQREARVQ
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