HK1 Antibody - N-terminal region : Biotin (ARP61059_P050-Biotin)

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.

SUMO2; SUMO3; STAU1; UBC; EGFR; SUMO1; NEDD8; MDM2; WDR61; UBA5; PARP6; NSFL1C; ARFGAP1; UBXN1; TWF2; FKBP9; PDCD10; PROSC; PLAA; GTF3C4; TUFM; TUBB2A; SGTA; RARS; PCNA; HEXB; HEXA; CAPN2; ASL; AHCY; PARK2; ATF2; VDAC1; LIG4; APP; AKT1; CDK2; SIRT7; ICT1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.