BID Antibody - C-terminal region : Biotin (ARP61037_P050-Biotin)

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) ; CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

AHCYL1; REL; MCL1; BCL2; BCL2L1; GZMB; CASP3; BAG3; CAV1; SQSTM1; VCP; UBQLN2; RPA2; RPA1; UBC; TUBB2B; FBN3; RBM48; CRNKL1; ZHX1; C14orf1; SETDB1; PLEKHM1; TLE1; GBP2; GAPDH; CRMP1; ITCH; BID; BCL2L2; CASP8; CASP10; YWHAB; BCL2A1; CSNK1E; CASP2; BAK1; CS

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

CDNA FLJ37476 fis, clone BRAWH2012827, highly similar to Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA EMBL BAG52933.1