TOP1 Antibody - N-terminal region: FITC (ARP61035_P050-FITC)
Product Specifications
Gene Name
Topoisomerase (DNA) I
Gene Aliases
TOPI
Gene ID
7150
Swiss Prot
P11387
Accession Number
NP_003277
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Target
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Partner Proteins
SUMO2; SUMO3; MDM2; UBC; SUMO1; ERG; RNF2; EED; SHFM1; CDK14; TARDBP; CDK2; HDAC9; EIF2AK2; PARP1; WHSC1; VCAM1; ITGA4; IL7R; VCP; PA2G4; NKX3-1; ESR1; RBM39; APP; UTP20; NCSTN; SUPT16H; RBM14; SF3B6; SRSF11; TPR; SNRPD1; S100A9; RPS14; HNRNPM; IK; HNRNPC
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
91kDa
Shipping Conditions
Wet Ice
Protein Length
765
NCBI Gene Symbol
TOP1
Protein Name
DNA topoisomerase 1
Nucleotide Accession Number
NM_003286
Curated Selection
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