CD44 Antibody - C-terminal region : Biotin (ARP61023_P050-Biotin)

Product Specifications

Gene Name

CD44 molecule (Indian blood group)

Gene Aliases

IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III

Gene ID

960

Swiss Prot

P16070

Accession Number

NP_001001391

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CD44

Target

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.

Partner Proteins

UBC; NF2; NEDD8; BAG1; DPP8; VHL; SRC; ANK1; ATF2; FMNL1; IQGAP1; SLC3A2; STAT3; ITGB1; FLOT2; EP300; CAV1; PRKCZ; ELAVL1; ARHGEF12; ARHGEF1; PKN1; DMP1; HMMR; TIAM1; ERBB4; VAV2; GARS; TGFBR2; TGFBR1; CD4; MMP7; SRGN; SPP1; LCK; IGFBP3; CD74; FYN; FGF2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

CD44 is strongly supported by BioGPS gene expression data to be expressed in MD-MB231

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.