HIST1H3A Antibody - N-terminal region: FITC (ARP60982_P050-FITC)
Product Specifications
Gene Name
Histone cluster 1, H3a
Gene Aliases
H3/A, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3C10, H3C11, H3C12, HIST1H3A
Gene ID
8350
Swiss Prot
P68431
Accession Number
NP_003520
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human HIST1H3A
Target
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Partner Proteins
WHSC1; SETD1A; FBLIM1; PRDM2; PRDM6; UBC; H2AFY; H2AFX; HIST1H1B; HIST1H1E; HIST1H1C; BAZ1B; HIST1H2AG; SMARCA5; HIST1H4A; HDAC2; UHRF1; L3MBTL2; GRB2; IRF1; HDAC11; AURKC; RPS6KA3; PAK1; ATXN1; ITGA4; env; CHAF1B; ASF1B; ASF1A; AURKB; CHAF1A; EP300; LRRK
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
HIST1H3A is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/mL
Homology
Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
15kDa
Shipping Conditions
Wet Ice
Protein Length
136
NCBI Gene Symbol
HIST1H3A
Protein Name
Histone H3.1
Nucleotide Accession Number
NM_003529
Curated Selection
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