HIST1H3A Antibody - N-terminal region : FITC (ARP60982_P050-FITC)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

WHSC1; SETD1A; FBLIM1; PRDM2; PRDM6; UBC; H2AFY; H2AFX; HIST1H1B; HIST1H1E; HIST1H1C; BAZ1B; HIST1H2AG; SMARCA5; HIST1H4A; HDAC2; UHRF1; L3MBTL2; GRB2; IRF1; HDAC11; AURKC; RPS6KA3; PAK1; ATXN1; ITGA4; env; CHAF1B; ASF1B; ASF1A; AURKB; CHAF1A; EP300; LRRK

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.