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ACTA1 Antibody - C-terminal region : FITC (ARP60968_P050-FITC)

Selected Variant

ARP60968_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Actin, alpha 1, skeletal muscle

Gene Aliases

ACTA, ASMA, CFTD, MPFD, NEM1, NEM2, NEM3, SHPM, CFTD1, CFTDM

Gene ID

58

Swiss Prot

P68133

Accession Number

NP_001091

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Target

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Partner Proteins

ABL1; TRIM63; TRIM55; CEP57; AMOT; UBC; SUMO3; CDKN2A; ACTG1; BRK1; ACTBL2; NCKAP1; LRCH3; MAPK14; DSTN; NMI; UBL4A; ABRA; ABLIM2; POLR1B; RRN3; HTRA2; PTPN22; ABLIM3; BTK; CCT2; TRAF3IP1; TCP1; SNCA; PARK2; LGALS3; SHC1; GSN; CDK2; CUL1; ISG15; YWHAZ; RE

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

Shipping Conditions

Wet Ice

Protein Length

377

NCBI Gene Symbol

ACTA1

NCBI GB Accession Number

ACTA1

Host or Source

Rabbit

Protein Name

Actin, alpha skeletal muscle

Nucleotide Accession Number

NM_001100

Peptide Sequence

STMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHR

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