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CAPN1 Antibody - middle region : Biotin (ARP60936_P050-Biotin)

Selected Variant

ARP60936_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Calpain 1, (mu/I) large subunit

Gene Aliases

CANP, muCL, CANP1, SPG76, CANPL1, muCANP

Gene ID

823

Swiss Prot

P07384

Accession Number

NP_005177

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Goat, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CAPN1

Target

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

Partner Proteins

UBC; TP53; SUMO2; GINS2; BZW2; YWHAQ; SLC9A3R1; RPS6KA1; RAP1GDS1; PFAS; PEPD; MVD; EIF6; HSPA9; GNS; GLS; GLA; GBP2; EIF4E; EEF2; ECHS1; CASP7; ASS1; LDHAL6B; GINS3; SMEK2; BCCIP; CNDP2; G6PD; HNRNPD; BAG3; SPTAN1; TINAGL1; PRMT5; CREG1; VIM; SLIT3; SH3B

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Goat: 79%; Horse: 93%; Human: 100%; Mouse: 80%; Pig: 86%; Rabbit: 79%; Rat: 83%; Sheep: 79%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

82kDa

Shipping Conditions

Wet Ice

Protein Length

714

NCBI Gene Symbol

CAPN1

NCBI GB Accession Number

CAPN1

Host or Source

Rabbit

Protein Name

Calpain-1 catalytic subunit

Nucleotide Accession Number

NM_005186

Peptide Sequence

EVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLE

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