PCSK9 Antibody : FITC (ARP60837_P050-FITC)
Product Specifications
Gene Name
Proprotein convertase subtilisin/kexin type 9
Gene Aliases
FH3, PC9, FHCL3, NARC1, LDLCQ1, NARC-1, HCHOLA3
Gene ID
255738
Swiss Prot
Q8NBP7
Accession Number
NP_777596
Host
Rabbit
Reactivity
Human, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP
Target
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3) .
Partner Proteins
TUBB6; UGGT1; AGK; RHOT1; DNAJC10; DNAJB11; PGRMC1; CDIPT; DNAJA2; STUB1; PDIA4; DNAJA3; SLC25A12; UBC; TRAF2; SLC25A1; RPL28; RCN1; LDLR; HSPB1; DNAJA1; SLC25A10; CLGN; BIRC2; BACE1; PCSK9
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%; Pig: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
74 kDa
Shipping Conditions
Wet Ice
Protein Length
692
NCBI Gene Symbol
PCSK9
NCBI GB Accession Number
PCSK9
Host or Source
Rabbit
Protein Name
Proprotein convertase subtilisin/kexin type 9
Nucleotide Accession Number
NM_174936
Peptide Sequence
RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP
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