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PCSK9 Antibody : Biotin (ARP60837_P050-Biotin)

Selected Variant

ARP60837_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Proprotein convertase subtilisin/kexin type 9

Gene Aliases

FH3, PC9, FHCL3, NARC1, LDLCQ1, NARC-1, HCHOLA3

Gene ID

255738

Swiss Prot

Q8NBP7

Accession Number

NP_777596

Host

Rabbit

Reactivity

Human, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP

Target

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3) .

Partner Proteins

TUBB6; UGGT1; AGK; RHOT1; DNAJC10; DNAJB11; PGRMC1; CDIPT; DNAJA2; STUB1; PDIA4; DNAJA3; SLC25A12; UBC; TRAF2; SLC25A1; RPL28; RCN1; LDLR; HSPB1; DNAJA1; SLC25A10; CLGN; BIRC2; BACE1; PCSK9

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Pig: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74 kDa

Shipping Conditions

Wet Ice

Protein Length

692

NCBI Gene Symbol

PCSK9

NCBI GB Accession Number

PCSK9

Host or Source

Rabbit

Protein Name

Proprotein convertase subtilisin/kexin type 9

Nucleotide Accession Number

NM_174936

Peptide Sequence

RITPPRYRADEYQPPDGGSLVEVYLLDTSIQSDHREIEGRVMVTDFENVP

Price

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