CYP7B1 Antibody - C-terminal region : Biotin (ARP60826_P050-Biotin)
Product Specifications
Gene Name
Cytochrome P450, family 7, subfamily B, polypeptide 1
Gene Aliases
CP7B, CBAS3, SPG5A
Gene ID
9420
Swiss Prot
O75881
Accession Number
NP_004811
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CYP7B1
Target
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Partner Proteins
UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
CYP7B1 is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Cow: 85%; Dog: 93%; Horse: 93%; Human: 100%; Pig: 86%; Rabbit: 85%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
58kDa
Shipping Conditions
Wet Ice
Protein Length
506
NCBI Gene Symbol
CYP7B1
NCBI GB Accession Number
CYP7B1
Host or Source
Rabbit
Protein Name
25-hydroxycholesterol 7-alpha-hydroxylase
Nucleotide Accession Number
NM_004820
Peptide Sequence
AMYYLLRHPEAMAAVRDEIDRLLQSTGQKKGSGFPIHLTREQLDSLICLE
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