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ACER1 Antibody - C-terminal region : HRP (ARP60813_P050-HRP)

Product Specifications

Gene Name

Alkaline ceramidase 1

Gene Aliases

ASAH3, ALKCDase1

Gene ID

125981

Swiss Prot

Q8TDN7

Accession Number

NP_597999

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ACER1

Target

ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ACER1 (ARP60813_P050-HRP) antibody

Protein Length

264

NCBI Gene Symbol

ACER1

NCBI GB Accession Number

ACER1

Host or Source

Rabbit

Protein Name

Alkaline ceramidase 1

Nucleotide Accession Number

NM_133492

Peptide Sequence

ITFPYGMVTMALVDANYEMPGETLKVRYWPRDSWPVGLPYVEIRGDDKDC

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