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ACER1 Antibody - C-terminal region : FITC (ARP60813_P050-FITC)

Selected Variant

ARP60813_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Alkaline ceramidase 1

Gene Aliases

ASAH3, ALKCDase1

Gene ID

125981

Swiss Prot

Q8TDN7

Accession Number

NP_597999

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ACER1

Target

ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

Shipping Conditions

Wet Ice

Protein Length

264

NCBI Gene Symbol

ACER1

NCBI GB Accession Number

ACER1

Host or Source

Rabbit

Protein Name

Alkaline ceramidase 1

Nucleotide Accession Number

NM_133492

Peptide Sequence

ITFPYGMVTMALVDANYEMPGETLKVRYWPRDSWPVGLPYVEIRGDDKDC

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