ACER1 Antibody - C-terminal region : Biotin (ARP60812_P050-Biotin)
Selected Variant
ARP60812_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Alkaline ceramidase 1
Gene Aliases
ASAH3, ALKCDase1
Gene ID
125981
Swiss Prot
Q8TDN7
Accession Number
NP_597999
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ACER1
Target
ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 92%; Guinea Pig: 75%; Human: 100%; Pig: 85%; Rabbit: 86%; Rat: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
31kDa
Shipping Conditions
Wet Ice
Protein Length
264
NCBI Gene Symbol
ACER1
NCBI GB Accession Number
ACER1
Host or Source
Rabbit
Protein Name
Alkaline ceramidase 1
Nucleotide Accession Number
NM_133492
Peptide Sequence
VNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVALTSWISD
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