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AKR1D1 Antibody - middle region : FITC (ARP60804_P050-FITC)

Selected Variant

ARP60804_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)

Gene Aliases

CBAS2, SRD5B1, 3o5bred

Gene ID

6718

Swiss Prot

P51857

Accession Number

NP_005980

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human AKR1D1

Target

The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta (4) -3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 86%; Rabbit: 100%; Rat: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

Shipping Conditions

Wet Ice

Protein Length

326

NCBI Gene Symbol

AKR1D1

NCBI GB Accession Number

AKR1D1

Host or Source

Rabbit

Protein Name

3-oxo-5-beta-steroid 4-dehydrogenase

Nucleotide Accession Number

NM_005989

Peptide Sequence

YVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGL

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