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IL27 Antibody - C-terminal region : Biotin (ARP60748_P050-Biotin)

Product Specifications

Gene Name

Interleukin 27

Gene Aliases

P28, IL30, IL-27, IL27A, IL-27A, IL27p28

Gene ID

246778

Swiss Prot

Q8NEV9

Accession Number

NP_663634

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human IL27

Target

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A) . It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR) .

Partner Proteins

IL27RA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

Shipping Conditions

Wet Ice

Protein Length

243

NCBI Gene Symbol

IL27

NCBI GB Accession Number

IL27

Host or Source

Rabbit

Protein Name

Interleukin-27 subunit alpha

Nucleotide Accession Number

NM_145659

Peptide Sequence

AQVSWPQLLSTYRLLHSLELVLSRAVRELLLLSKAGHSVWPLGFPTLSPQ

Subunit

Alpha

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