IL18 Antibody - C-terminal region : Biotin (ARP60740_P050-Biotin)
Selected Variant
ARP60740_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Interleukin 18 (interferon-gamma-inducing factor)
Gene Aliases
IGIF, IL-18, IL-1g, IL1F4
Gene ID
3606
Swiss Prot
Q14116
Accession Number
NP_001553
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human IL18
Target
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Partner Proteins
CASK; UBC; IL1RL2; IL18RAP; IL18R1; IL18BP; CASP4; CASP3; CASP1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
IL18 is supported by BioGPS gene expression data to be expressed in HeLa
Concentration
0.5 mg/ml
Homology
Human: 100%; Mouse: 79%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
18kDa
Shipping Conditions
Wet Ice
Protein Length
193
NCBI Gene Symbol
IL18
NCBI GB Accession Number
IL18
Host or Source
Rabbit
Protein Name
Interleukin-18
Nucleotide Accession Number
NM_001562
Peptide Sequence
IIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRS
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