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GFM2 Antibody - C-terminal region : Biotin (ARP60546_P050-Biotin)

Selected Variant

ARP60546_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

G elongation factor, mitochondrial 2

Gene Aliases

RRF, EFG2, RRF2, MRRF2, hEFG2, MST027, RRF2mt, EF-G2mt, MSTP027, mEF-G 2

Gene ID

84340

Swiss Prot

Q969S9

Accession Number

NP_115756

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GFM2

Target

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.

Partner Proteins

TRIM9; BANP; VPS52; TRIM27; UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Horse: 86%; Human: 100%; Pig: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

Shipping Conditions

Wet Ice

Protein Length

779

NCBI Gene Symbol

GFM2

NCBI GB Accession Number

GFM2

Host or Source

Rabbit

Protein Name

Ribosome-releasing factor 2, mitochondrial

Nucleotide Accession Number

NM_032380

Peptide Sequence

TVGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVE

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