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Vps25 Antibody - C-terminal region : FITC (ARP60528_P050-FITC)

Selected Variant

ARP60528_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Vacuolar protein sorting 25 homolog (S. cerevisiae)

Gene ID

681059

Swiss Prot

P0C0A1

Accession Number

NP_001166922

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Vps25

Target

Vps25 is a component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

19kDa

Shipping Conditions

Wet Ice

Protein Length

176

NCBI Gene Symbol

VPS25

NCBI GB Accession Number

Vps25

Host or Source

Rabbit

Protein Name

Vacuolar protein-sorting-associated protein 25

Nucleotide Accession Number

NM_001173451

Peptide Sequence

LYELTSGEDTEEEEFHGLDEATLLRALQALQQEHKAEIITVSDGRGVKFF

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