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MRPL45 Antibody - C-terminal region : HRP (ARP60476_P050-HRP)

Product Specifications

Gene Name

Mitochondrial ribosomal protein L45

Gene Aliases

L45mt, MRP-L45

Gene ID

84311

Swiss Prot

Q9BRJ2

Accession Number

NP_115727

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MRPL45

Target

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.

Partner Proteins

TRIM23; UBC; C1QBP; TMEM177; MRPL24; MARCKSL1; MRPL9; MRPL11; MRPL32; MRPL38; MRPL47; SYNJ2BP; MRPL50; MRPL51; MRPL37; MRPL15; MRPL13; ZC3H4; HNRNPR; MRPL19; SDHB; ILF3; CUL3; ICT1; KBTBD7; G3BP1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 75%; Human: 100%; Mouse: 91%; Rat: 82%; Zebrafish: 75%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-MRPL45 (ARP60476_P050-HRP) antibody

Protein Length

306

NCBI Gene Symbol

MRPL45

NCBI GB Accession Number

MRPL45

Host or Source

Rabbit

Protein Name

39S ribosomal protein L45, mitochondrial

Nucleotide Accession Number

NM_032351

Peptide Sequence

YGSWRMHTKIVPPWAPPKQPILKTVMIPGPQLKPEEEYEEAQGEAQKPQL

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