MRPL45 Antibody - C-terminal region : Biotin (ARP60476_P050-Biotin)

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.

TRIM23; UBC; C1QBP; TMEM177; MRPL24; MARCKSL1; MRPL9; MRPL11; MRPL32; MRPL38; MRPL47; SYNJ2BP; MRPL50; MRPL51; MRPL37; MRPL15; MRPL13; ZC3H4; HNRNPR; MRPL19; SDHB; ILF3; CUL3; ICT1; KBTBD7; G3BP1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.