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MICB Antibody - N-terminal region: FITC (ARP60344_P050-FITC)

Product Specifications

Gene Name

MHC class I polypeptide-related sequence B

Gene Aliases

PERB11.2

Gene ID

4277

Swiss Prot

Q29980

Accession Number

NP_005922

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MICB

Target

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Partner Proteins

UBC; ZCCHC8; ELAVL1; KLRK1; KLRC4

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/mL

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42 kDa

Shipping Conditions

Wet Ice

Protein Length

383

NCBI Gene Symbol

MICB

Protein Name

MHC class I polypeptide-related sequence B

Nucleotide Accession Number

NM_005931.4Â

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