MARCKS Antibody - C-terminal region : HRP (ARP60326_P050-HRP)

Product Specifications

Gene Name

Myristoylated alanine-rich protein kinase C substrate

Gene Aliases

MACS, 80K-L, PKCSL, PRKCSL

Gene ID

4082

Swiss Prot

P29966

Accession Number

NP_002347

Host

Rabbit

Reactivity

Human, Cow, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS

Target

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Partner Proteins

UBC; TUBGCP3; UBQLN2; RPA2; PRKACA; PARK2; PKN1; PRKCB; HCVgp1; ATF2; PRKCZ; HSP90AA1; HNRNPU; DFFB; DBN1; SPP1; CDK4; CDK2; CDK1; CCNE1; ELAVL1; EBNA-LP; Mapk13; TOB1; PRKCA; NMT1; CTSB; CALM3; CALM2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

MARCKS is strongly supported by BioGPS gene expression data to be expressed in SHSY5Y

Concentration

0.5 mg/ml

Homology

Cow: 93%; Human: 100%; Rabbit: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.