MARCKS Antibody - C-terminal region: FITC (ARP60326_P050-FITC)
Product Specifications
Gene Name
Myristoylated alanine-rich protein kinase C substrate
Gene Aliases
MACS, 80K-L, PKCSL, PRKCSL
Gene ID
4082
Swiss Prot
P29966
Accession Number
NP_002347
Host
Rabbit
Reactivity
Human, Cow, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human MARCKS
Target
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Partner Proteins
UBC; TUBGCP3; UBQLN2; RPA2; PRKACA; PARK2; PKN1; PRKCB; HCVgp1; ATF2; PRKCZ; HSP90AA1; HNRNPU; DFFB; DBN1; SPP1; CDK4; CDK2; CDK1; CCNE1; ELAVL1; EBNA-LP; Mapk13; TOB1; PRKCA; NMT1; CTSB; CALM3; CALM2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
MARCKS is strongly supported by BioGPS gene expression data to be expressed in SHSY5Y
Concentration
0.5 mg/mL
Homology
Cow: 93%; Human: 100%; Rabbit: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
31kDa
Shipping Conditions
Wet Ice
Protein Length
332
NCBI Gene Symbol
MARCKS
Protein Name
Myristoylated alanine-rich C-kinase substrate
Nucleotide Accession Number
NM_002356
Curated Selection
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