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MAPKAPK2 Antibody - middle region: FITC (ARP60320_P050-FITC)

Product Specifications

Gene Name

Mitogen-activated protein kinase-activated protein kinase 2

Gene Aliases

MK2, MK-2, MAPKAP-K2

Gene ID

9261

Swiss Prot

Q16644

Accession Number

NP_004626

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MAPKAPK2

Target

MAPKAPK2 is a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.

Partner Proteins

PIAS2; DDX5; MAPK14; AKT1; HSPB1; MAPKAPK2; UBC; Ube2j1; TCF3; DES; MAP2K6; MAPK11; MAPK3; PABPC1; HNRNPA0; PARN; LIMK1; HSF1; CHEK1; CDC25B; ALOX5; ZFP36L1; ESR1; COPS5; CUL3; MAPKAPK5; MAPK1; ELAVL1; PHC2; CSNK2B; ARPC5; EEF2K; BAG2; YWHAZ; SRF; SHC1; E

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

Shipping Conditions

Wet Ice

Protein Length

370

NCBI Gene Symbol

MAPKAPK2

Protein Name

MAP kinase-activated protein kinase 3

Nucleotide Accession Number

NM_004635

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