MAPKAPK2 Antibody - middle region: Biotin (ARP60320_P050-Biotin)
Product Specifications
Gene Name
Mitogen-activated protein kinase-activated protein kinase 2
Gene Aliases
MK2, MK-2, MAPKAP-K2
Gene ID
9261
Swiss Prot
Q16644
Accession Number
NP_004626
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human MAPKAPK2
Target
MAPKAPK2 is a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.
Partner Proteins
PIAS2; DDX5; MAPK14; AKT1; HSPB1; MAPKAPK2; UBC; Ube2j1; TCF3; DES; MAP2K6; MAPK11; MAPK3; PABPC1; HNRNPA0; PARN; LIMK1; HSF1; CHEK1; CDC25B; ALOX5; ZFP36L1; ESR1; COPS5; CUL3; MAPKAPK5; MAPK1; ELAVL1; PHC2; CSNK2B; ARPC5; EEF2K; BAG2; YWHAZ; SRF; SHC1; E
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
42kDa
Shipping Conditions
Wet Ice
Protein Length
370
NCBI Gene Symbol
MAPKAPK2
Protein Name
MAP kinase-activated protein kinase 3
Nucleotide Accession Number
NM_004635
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