MAP4 Antibody - N-terminal region: HRP (ARP60314_P050-HRP)
Product Specifications
Gene Name
Microtubule-associated protein 4
Gene Aliases
DKFZp779A1753, MGC8617
Gene ID
4134
Swiss Prot
P27816
Accession Number
NP_002366
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4
Target
MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU) . This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.
Partner Proteins
UBC; LGR4; RPA3; RPA2; RPA1; LSM8; WDHD1; HNRNPR; PDCD6; PPP4R1; MTA2; POLR2C; POLR2A; IARS; HNRNPF; EIF2S1; CSTF2; COG7; TARDBP; BAG3; ERBB2IP; SNTA1; LDLR; IL7R; FN1; TRAF3IP1; RPS20; GRK5; EPS15; AP2M1; USP21; CUL4A; POT1; ISG15; TERF1; SIRT7; SH3KBP1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
121kDa
Shipping Conditions
Wet Ice
Protein Length
1152
NCBI Gene Symbol
MAP4
Protein Name
Microtubule-associated protein 4
Nucleotide Accession Number
NM_002375
Curated Selection
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