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MAP4 Antibody - N-terminal region : HRP (ARP60314_P050-HRP)

Selected Variant

ARP60314_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Microtubule-associated protein 4

Gene Aliases

DKFZp779A1753, MGC8617

Gene ID

4134

Swiss Prot

P27816

Accession Number

NP_002366

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4

Target

MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU) . This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.

Partner Proteins

UBC; LGR4; RPA3; RPA2; RPA1; LSM8; WDHD1; HNRNPR; PDCD6; PPP4R1; MTA2; POLR2C; POLR2A; IARS; HNRNPF; EIF2S1; CSTF2; COG7; TARDBP; BAG3; ERBB2IP; SNTA1; LDLR; IL7R; FN1; TRAF3IP1; RPS20; GRK5; EPS15; AP2M1; USP21; CUL4A; POT1; ISG15; TERF1; SIRT7; SH3KBP1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

121kDa

Shipping Conditions

Wet Ice

Protein Length

1152

NCBI Gene Symbol

MAP4

NCBI GB Accession Number

MAP4

Host or Source

Rabbit

Protein Name

Microtubule-associated protein 4

Nucleotide Accession Number

NM_002375

Peptide Sequence

LKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPK

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