MAP3K10 Antibody - C-terminal region: FITC (ARP60309_P050-FITC)
Product Specifications
Gene Name
Mitogen-activated protein kinase kinase kinase 10
Gene Aliases
MST, MLK2, MEKK10
Gene ID
4294
Swiss Prot
Q02779
Accession Number
NP_002437
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human MAP3K10
Target
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Partner Proteins
MAPK9; MAPK1; MAP3K10; MAPK14; GARS; COPS2; KIAA1804; ABL2; SH3RF1; CNKSR1; YWHAE; RACGAP1; KIF3A; DNM1L; KIF3B; DLG4; KIFAP3; MAP2K4; TUBB; PHB; HTT; CLTC; CDC42; CEACAM1; HGS; DNM1; KRTAP3-4P; KIF17; MAPK8IP2; MAPK8IP1; RAC1; HPCA; NEUROD1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
104kDa
Shipping Conditions
Wet Ice
Protein Length
954
NCBI Gene Symbol
MAP3K10
Protein Name
Mitogen-activated protein kinase kinase kinase 10
Nucleotide Accession Number
NM_002446
Curated Selection
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