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CD55 Antibody - middle region : HRP (ARP60155_P050-HRP)

Selected Variant

ARP60155_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

CD55 molecule, decay accelerating factor for complement (Cromer blood group)

Gene Aliases

CR, TC, DAF, CROM, CHAPLE

Gene ID

1604

Swiss Prot

P08174

Accession Number

NP_000565

Host

Rabbit

Reactivity

Human, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CD55

Target

This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF) ; binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) . Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.

Partner Proteins

UBC; NDUFB7; NDUFS7; TIMM50; INF2; SYNJ2BP; PTCD3; PTRH2; MRPL4; SLC25A24; RAB31; ZMPSTE24; PICALM; SLC12A4; SLC2A1; S100A10; MPV17; MAN2A1; GNAI3; ATP6V1E1; GPLD1; CD97; CD14; LCK; FYN; CD55; CR1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 79%; Horse: 79%; Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

Shipping Conditions

Wet Ice

Protein Length

381

NCBI Gene Symbol

CD55

NCBI GB Accession Number

CD55

Host or Source

Rabbit

Protein Name

Complement decay-accelerating factor

Nucleotide Accession Number

NM_000574

Peptide Sequence

PGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI

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