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CYP51A1 Antibody - N-terminal region : HRP (ARP60153_P050-HRP)

Selected Variant

ARP60153_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Cytochrome P450, family 51, subfamily A, polypeptide 1

Gene Aliases

LDM, CP51, CYP51, CYPL1, P450L1, P450-14DM

Gene ID

1595

Swiss Prot

Q16850

Accession Number

NP_000777

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CYP51A1

Target

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; ZNF420; ELAVL1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

Shipping Conditions

Wet Ice

Protein Length

509

NCBI Gene Symbol

CYP51A1

NCBI GB Accession Number

CYP51A1

Host or Source

Rabbit

Protein Name

Lanosterol 14-alpha demethylase

Nucleotide Accession Number

NM_000786

Peptide Sequence

TYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQ

Price

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