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COL4A6 Antibody - middle region : Biotin (ARP60012_P050-Biotin)

Selected Variant

ARP60012_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Collagen, type IV, alpha 6

Gene Aliases

DFNX6, DELXq22.3, CXDELq22.3

Gene ID

1288

Swiss Prot

Q14031

Accession Number

NP_001838

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human COL4A6

Target

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

Partner Proteins

APP; VHL; HABP2; MATN2; SERPINE2; OSM; FBLN2; FN1; DCN; CD93; MMP9

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

161kDa

Shipping Conditions

Wet Ice

Protein Length

1691

NCBI Gene Symbol

COL4A6

NCBI GB Accession Number

COL4A6

Host or Source

Rabbit

Protein Name

Collagen alpha-6 (IV) chain

Nucleotide Accession Number

NM_001847

Peptide Sequence

GIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN

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