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CLN5 Antibody - C-terminal region : Biotin (ARP59986_P050-Biotin)

Selected Variant

ARP59986_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Ceroid-lipofuscinosis, neuronal 5

Gene Aliases

NCL

Gene ID

1203

Swiss Prot

O75503

Accession Number

NP_006484

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CLN5

Target

This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Partner Proteins

ARHGAP36; FBXO27; SPNS1; SFXN3; SLC25A22; SEC61A1; FBXO6; PHGDH; GANAB; OS9; CDIPT; SLC25A13; CDS2; SLC25A11; XPO1; SLC25A1; SEL1L; RPN1; RCN2; HMGCS1; DBH; CLN5; CLGN; CANX; CALU; CALR; ATP2A2; ATP1A3; ARF4; SLC25A6; SLC25A5; SLC25A4; Dlg4; UBC; KRT8

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 86%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39 kDa

Shipping Conditions

Wet Ice

Protein Length

358

NCBI Gene Symbol

CLN5

NCBI GB Accession Number

CLN5

Host or Source

Rabbit

Protein Name

Ceroid-lipofuscinosis neuronal protein 5

Nucleotide Accession Number

NM_006493.2

Peptide Sequence

DNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKN

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