CLN5 Antibody - C-terminal region : Biotin (ARP59986_P050-Biotin)
Selected Variant
ARP59986_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Ceroid-lipofuscinosis, neuronal 5
Gene Aliases
NCL
Gene ID
1203
Swiss Prot
O75503
Accession Number
NP_006484
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CLN5
Target
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Partner Proteins
ARHGAP36; FBXO27; SPNS1; SFXN3; SLC25A22; SEC61A1; FBXO6; PHGDH; GANAB; OS9; CDIPT; SLC25A13; CDS2; SLC25A11; XPO1; SLC25A1; SEL1L; RPN1; RCN2; HMGCS1; DBH; CLN5; CLGN; CANX; CALU; CALR; ATP2A2; ATP1A3; ARF4; SLC25A6; SLC25A5; SLC25A4; Dlg4; UBC; KRT8
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Cow: 77%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 86%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
39 kDa
Shipping Conditions
Wet Ice
Protein Length
358
NCBI Gene Symbol
CLN5
NCBI GB Accession Number
CLN5
Host or Source
Rabbit
Protein Name
Ceroid-lipofuscinosis neuronal protein 5
Nucleotide Accession Number
NM_006493.2
Peptide Sequence
DNETGIYYETWNVKASPEKGAETWFDSYDCSKFVLRTFNKLAEFGAEFKN
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