AP1B1 Antibody - C-terminal region: Biotin (ARP59977_P050-Biotin)
Product Specifications
Gene Name
Adaptor-related protein complex 1, beta 1 subunit
Gene Aliases
ADTB1, BAM22, KIDAR, AP105A, CLAPB2
Gene ID
162
Swiss Prot
Q10567
Accession Number
NP_001118
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human AP1B1
Target
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
Partner Proteins
UBC; EGFR; RPA3; RPA2; RPA1; TRMT61A; DIABLO; INTS9; TBC1D2; TRIP10; ABCE1; PPP6R3; NTRK2; AP1G1; VCP; BARD1; AP1M1; AP1S2; AP1S1; EPS15; AP2M1; EPN1; SNAP91; CLINT1; COPS5; CUL3; SHBG; CDK2; SIRT7; SNCA; ATF7IP; KIF13A; ATM; AP1M2; PIP5K1C; BUB1B; BUB1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
104kDa
Shipping Conditions
Wet Ice
Protein Length
949
NCBI Gene Symbol
AP1B1
Protein Name
AP-1 complex subunit beta-1
Nucleotide Accession Number
NM_001127
Curated Selection
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