AP1B1 Antibody - C-terminal region : Biotin (ARP59977_P050-Biotin)

Product Specifications

Gene Name

Adaptor-related protein complex 1, beta 1 subunit

Gene Aliases

ADTB1, BAM22, KIDAR, AP105A, CLAPB2

Gene ID

162

Swiss Prot

Q10567

Accession Number

NP_001118

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AP1B1

Target

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.

Partner Proteins

UBC; EGFR; RPA3; RPA2; RPA1; TRMT61A; DIABLO; INTS9; TBC1D2; TRIP10; ABCE1; PPP6R3; NTRK2; AP1G1; VCP; BARD1; AP1M1; AP1S2; AP1S1; EPS15; AP2M1; EPN1; SNAP91; CLINT1; COPS5; CUL3; SHBG; CDK2; SIRT7; SNCA; ATF7IP; KIF13A; ATM; AP1M2; PIP5K1C; BUB1B; BUB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.