AP2A1 Antibody - C-terminal region : Biotin (ARP59972_P050-Biotin)

Product Specifications

Gene Name

Adaptor-related protein complex 2, alpha 1 subunit

Gene Aliases

ADTAA, CLAPA1, AP2-ALPHA

Gene ID

160

Swiss Prot

O95782

Accession Number

NP_570603

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human AP2A1

Target

This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma) . The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Partner Proteins

SUMO2; SUMO3; UBC; EGFR; EPHA2; ABCB11; RPA3; RPA2; RPA1; BIN1; PIN1; GRB2; PPP6R3; RNF11; ARRB1; MMS19; SMAD9; ITGA4; FN1; DAB2; VCAM1; PICALM; AP2A2; SHC1; MYO6; GRK5; EPS15; CRK; AP2M1; ABL1; AMPH; Epn1; RALBP1; REPS2; SYNJ1; SHBG; BRCA1; ARRB2; Edc4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.