ADSL Antibody - middle region: Biotin (ARP59971_P050-Biotin)
Product Specifications
Gene Name
Adenylosuccinate lyase
Gene Aliases
ASL, AMPS, ASASE
Gene ID
158
Swiss Prot
P30566
Accession Number
NP_000017
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ADSL
Target
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
CALCOCO2; REL; UBC; PDE12; BTF3L4; NPLOC4; EHD4; UBQLN2; NT5C2; WDR4; PAIP1; PLIN3; SAE1; OXSR1; API5; XPNPEP1; WARS; RAD23B; TWF1; DNAJB1; GTF2I; EIF1AX; DRG2; CTSC; NOV; TYMS; SUMO1; DDA1; USP15; USP4
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 86%; Sheep: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
55kDa
Shipping Conditions
Wet Ice
Protein Length
484
NCBI Gene Symbol
ADSL
Protein Name
Adenylosuccinate lyase
Nucleotide Accession Number
NM_000026
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NBP2-69680 10 mg
Goat Polyclonal Goat anti-Avian IgM Fc fragment Secondary Antibody (Azide Free)
Ask
View Details 