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CACNA2D4 Antibody - C-terminal region : FITC (ARP59811_P050-FITC)

Selected Variant

ARP59811_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Calcium channel, voltage-dependent, alpha 2/delta subunit 4

Gene Aliases

RCD4

Gene ID

93589

Swiss Prot

Q7Z3S7

Accession Number

NP_758952

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CACNA2D4

Target

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 85%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

128kDa

Shipping Conditions

Wet Ice

Protein Length

1137

NCBI Gene Symbol

CACNA2D4

NCBI GB Accession Number

CACNA2D4

Host or Source

Rabbit

Protein Name

Voltage-dependent calcium channel subunit alpha-2/delta-4

Nucleotide Accession Number

NM_172364

Peptide Sequence

MAFLGTRAGLLRSSLFVGSEKVSDRKFLTPEDEASVFTLDRFPLWYRQAS

Subunit

Alpha-2/delta-4

Price

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