MYOC Antibody - N-terminal region : Biotin (ARP59771_P050-Biotin)
Selected Variant
ARP59771_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Myocilin, trabecular meshwork inducible glucocorticoid response
Gene Aliases
GPOA, JOAG, TIGR, GLC1A, JOAG1
Gene ID
4653
Swiss Prot
Q99972
Accession Number
NP_000252.1
Host
Rabbit
Reactivity
Human, Rat, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human MYOC
Target
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR) . The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Guinea Pig: 86%; Human: 100%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
Shipping Conditions
Wet Ice
Protein Length
344
NCBI Gene Symbol
MYOC
NCBI GB Accession Number
MYOC
Host or Source
Rabbit
Protein Name
Myocilin
Nucleotide Accession Number
NM_000261.1
Peptide Sequence
QLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKS
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