CANX Antibody - C-terminal region : Biotin (ARP59755_P050-Biotin)

Product Specifications

Gene Name

Calnexin

Gene Aliases

CNX, P90, IP90

Gene ID

821

Swiss Prot

P27824

Accession Number

NP_001737

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CANX

Target

This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER) -associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

Partner Proteins

ERLIN2; HUWE1; UBC; TRAF6; SUMO2; TOR1A; STAU1; MDM2; LGR4; WWOX; NPHS1; RPA3; RPA2; RPA1; SUZ12; RNF2; BMI1; FBXO6; PTGIR; ADRB2; PDIA3; CLN5; YIPF3; SMURF2; env; PGRMC1; BCAP31; UBL4A; SERPINA1; MTNR1A; CSNK2A1; ATF2; CFTR; VCP; PKD2; LDLR; ASGR1; KCNH2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

CANX is strongly supported by BioGPS gene expression data to be expressed in A549

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.