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Rassf5 Antibody - C-terminal region : FITC (ARP59675_P050-FITC)

Selected Variant

ARP59675_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Ras association (RalGDS/AF-6) domain family member 5

Gene Aliases

No, Nor, Rapl, Maxp1, Nore1, Nore1A, Nore1B, 1300019G20Rik

Gene ID

54354

Swiss Prot

Q5EBH1

Accession Number

NP_061220

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Rassf5

Target

Rassf5 is a potental tumor suppressor. It seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. It may be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.

Partner Proteins

Hras

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

Shipping Conditions

Wet Ice

Protein Length

413

NCBI Gene Symbol

RASSF5

NCBI GB Accession Number

Rassf5

Host or Source

Rabbit

Protein Name

Ras association domain-containing protein 5

Nucleotide Accession Number

NM_018750

Peptide Sequence

SFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQK

Price

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