SPR Antibody - C-terminal region : Biotin (ARP59628_P050-Biotin)

Product Specifications

Gene Name

Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

Gene Aliases

SDR38C1

Gene ID

6697

Swiss Prot

P35270

Accession Number

NP_003115

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SPR

Target

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4) . Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

Partner Proteins

UBC; YWHAQ; MRPL53; SRPRB; SUGP1; SBDS; AHCYL1; SCO2; RAD23B; PPM1G; NDUFA2; IDH3G; CRK; ASS1; CAMK2G

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

SPR is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Dog: 79%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.