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CORT Antibody - N-terminal region : Biotin (ARP59541_P050-Biotin)

Product Specifications

Gene Name

Cortistatin

Gene Aliases

SST2, CST-14, CST-17, CST-29

Gene ID

1325

Swiss Prot

O00230

Accession Number

NP_001293

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CORT

Target

This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739.

Partner Proteins

MRGPRX2; GHSR; SSTR5; SSTR4; SSTR3; SSTR2; SSTR1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CORT is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

2kDa

Shipping Conditions

Wet Ice

Protein Length

155

NCBI Gene Symbol

CORT

NCBI GB Accession Number

CORT

Host or Source

Rabbit

Protein Name

Cortistatin

Nucleotide Accession Number

NM_001302

Peptide Sequence

MPLSPGLLLLLLSGATATAALPLEGGPTGRDSEHMQEAAGIRKSSLLTFL

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